Peer-reviewed veterinary case report
Painful skin swelling from lymphangiosarcoma in young Doberman dog
By Diessler, M E et al.·Published in Journal of veterinary medicine. A, Physiology, pathology, clinical medicine·2003·Institute of Pathology·View original on PubMed →
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Original publication title: Cutaneous lymphangiosarcoma in a young dog: clinical, anatomopathological and lectinhistochemical description.
- Species:
- dog
Plain-English summary
A 1-year-old female Doberman Pinscher was brought in for a painful swelling under her left front leg. After examining the tissue, the vet diagnosed her with a rare tumor called lymphangiosarcoma, which affects the lymphatic system. Unfortunately, the dog was euthanized due to the severity of the condition, and further examination showed that the cancer had spread to her lymph nodes. This case highlights the challenges in diagnosing lymphangiosarcoma compared to similar tumors, but it also provides insights that could help in future diagnoses.
People also search for: dog tumor under leg · Doberman Pinscher cancer symptoms · lymphangiosarcoma treatment in dogs
Abstract
Lymphangiosarcoma is a rare tumour in domestic animals arising from lymphatic endothelial cells. Occasionally, microscopic differentiation with haemangiosarcoma may be difficult. The aim of the present study was to describe a lymphangiosarcoma in a 1-year-old female Doberman Pinscher dog and to characterize its lectinhistochemical binding pattern as compared with that of haemangiosarcoma. The dog was presented because of a cutaneous painful swelling located in the left axilla. Histological diagnosis confirmed lymphangiosarcoma. The dog was killed. Necropsy revealed mediastinal lymph nodes' involvement. Twenty lectins were tested in tissue sections of this case as well as in four haemangiosarcomas from other dogs. Staining intensity was issued upon optical density determinations. Percentage of lectinhistochemical staining area was also conducted. RCA-I showed the most intense and wide distributed labelling pattern for lymphangiosarcoma. PHA-E was the counterpart for haemangiosarcoma. Should similar results be obtained in further studies, such differences could aid in the differential diagnosis between lymphangiosarcoma and haemangiosarcoma when histological pictures were not conclusive.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/15109239/