Peer-reviewed veterinary case report
Dog with skin myxosarcoma and lung metastases explained
By Headley, S A et al.·Published in Journal of comparative pathology·2011·Department of Basic Veterinary Sciences University of Helsinki·View original on PubMed →
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Original publication title: Cutaneous myxosarcoma with pulmonary metastases in a dog.
- Species:
- dog
Plain-English summary
A 13-year-old dog was found to have a large lump under the skin near its shoulder, along with a smaller nodule in the belly and a mass at a previous fracture site. After taking X-rays, the vet discovered several nodules in the dog's lungs, indicating that the cancer had spread. The diagnosis was cutaneous myxosarcoma, a type of skin cancer that can invade other tissues. Unfortunately, the presence of lung nodules suggests a more serious condition, and treatment options would depend on the overall health of the dog and the extent of the disease.
People also search for: dog skin lump · dog lung nodules · cutaneous myxosarcoma treatment · old dog cancer symptoms · dog cancer prognosis
Abstract
The pathological findings in a 13-year-old dog with cutaneous myxosarcoma with pulmonary metastases are described. Grossly, there was a large subcutaneous mass in the right scapular region, a smaller nodule in the caudal abdominal region and a fibrotic mass at a fracture site in the right hindlimb. Radiographic examination revealed several pulmonary nodules. Microscopical evaluation revealed a myxosarcoma characterized by the proliferation of spindle to stellate cells with multiple prominent nucleoli and vascular invasion. The neoplastic cells were haphazardly arranged in a mucopolysaccharide matrix. Immunohistochemically, the neoplastic cells expressed vimentin, but not cytokeratin or glial fibrillary acidic protein. There was restricted expression of desmin, smooth muscle actin and S-100 protein.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/21310431/