Peer-reviewed veterinary case report
Rare skin cancer tumor on a dog's hock with hair loss
By Rissi, D R·Published in Journal of comparative pathology·2019·Department of Pathology and Athens Veterinary Diagnostic Laboratory, United States·View original on PubMed →
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Original publication title: Cutaneous Pilomatrical Carcinosarcoma in a Dog.
- Species:
- dog
Plain-English summary
A 9-year-old mixed-breed dog was brought in with a lump on the left back leg that had some hair loss around it. The vet found that this lump was a rare type of skin tumor called pilomatrical carcinosarcoma, which is a malignant growth. The tumor had both cancerous and sarcomatous (connective tissue) features. While the abstract does not specify treatment details, tumors like this often require surgical removal, and early detection can improve outcomes.
People also search for: dog skin lump treatment · pilomatrical carcinosarcoma in dogs · dog tumor removal recovery
Abstract
Malignant pilomatricomas are uncommon cutaneous neoplasms in veterinary and human medicine. Pilomatrical carcinosarcoma is a rare subset of malignant pilomatricoma that has been described in man. This article reports a neoplasm with morphological features of pilomatrical carcinosarcoma in a dog. The nodular neoplasm occurred on the left lateral hock and was partially alopecic. Microscopically, the tumour was composed of a cystic carcinomatous component surrounding areas of abrupt keratinization and a sarcomatous component exhibiting bundles of spindle cells and irregular, scalloped areas of mineralized and non-mineralized osteoid matrix. The carcinomatous and sarcomatous areas were immunoreactive for pan-cytokeratin and vimentin, respectively, while immunoreactivity for e-cadherin was restricted to the carcinomatous component of the neoplasm. The unique morphological features of this tumour were similar to those described in human pilomatrical carcinosarcoma.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/31375155/