Peer-reviewed veterinary case report
Small skin plasma cell tumor with Mott cells in a dog
By Auch, Cheryl L & Michael, Alyona·Published in Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·2024·College of Veterinary Medicine, United States·View original on PubMed →
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Original publication title: Cutaneous plasmacytoma with Mott cell differentiation in a dog.
- Species:
- dog
Plain-English summary
A 9-year-old spayed female Yorkshire Terrier had a small mass between her toes that was evaluated by a vet. The tests showed that the mass was a type of skin tumor called a cutaneous plasmacytoma, which is made up of abnormal plasma cells. The tumor was completely removed through surgery, and it was found to have specific characteristics that helped identify it. This type of tumor is rare in dogs, but in this case, the surgery was successful, and the dog was expected to recover well.
People also search for: dog toe mass · Yorkshire Terrier skin tumor · cutaneous plasmacytoma treatment
Abstract
Cytologic evaluation of aspirate slides from a small, <1-cm, interdigital mass on a 9-y-old, spayed female Yorkshire Terrier revealed a proliferation of discrete, round cells containing few-to-many, variably sized, round, eosinophilic, cytoplasmic inclusions. The top differentials based on the cytologic findings were either a plasma cell tumor or a B-cell lymphoma with Mott cell differentiation. The unencapsulated, well-demarcated, multilobulated round-cell neoplasm was completely excised. Immunohistochemical stains were performed to further characterize the neoplasm, which had immunolabeling for multiple myeloma oncogene 1 and vimentin, but did not react with CD3, CD20, melan A, or ionized calcium-binding adapter molecule 1, nor with a Giemsa special stain. Ultrastructurally, the cytoplasmic granules had Russell body-like morphology. A solitary, cutaneous plasmacytoma with Mott cell differentiation has not been described previously in veterinary medicine, to our knowledge.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/38842410/