Peer-reviewed veterinary case report
Dog with skin lumps diagnosed with T cell lymphoma by flow cytometry
By Baines, S J et al.·Published in The Veterinary record·2000·Department of Clinical Veterinary Medicine, United Kingdom·View original on PubMed →
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Original publication title: Cutaneous T cell lymphoma mimicking cutaneous histiocytosis: differentiation by flow cytometry.
- Species:
- dog
Plain-English summary
A 2-year-old female Labrador mix was brought to the vet with multiple skin lumps that looked like a skin problem called cutaneous histiocytosis. Over a month, she developed swollen lymph nodes and masses in her muscles and behind her eyes. Tests, including fine needle aspirations and biopsies, eventually showed that she had a type of cancer called CD8+ T cell lymphoma. This diagnosis helped the vet determine the best treatment plan for her condition.
People also search for: dog skin lumps · Labrador lymphoma treatment · swollen lymph nodes in dogs · cutaneous histiocytosis vs lymphoma in dogs
Abstract
A two-year-old, neutered female cross-bred labrador had multiple cutaneous nodules, biopsies of which revealed pathological changes consistent with cutaneous histiocytosis. During a period of one month the dog developed multicentric lymphadenopathy, a retrobulbar mass and masses within the quadriceps and cervical muscles. Fine needle aspiration cytology of the cutaneous nodules and lymph nodes and histological examination of the cutaneous nodules and muscle masses suggested the presence of lymphoblastic lymphoma. A definitive diagnosis of CD8+ T cell lymphoma was achieved by immunophenotyping the tumour cells by flow cytometry.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/10975346/