Peer-reviewed veterinary case report
Cat with severe red cell aplasia treated successfully
By Mischke, R·Published in Berliner und Munchener tierarztliche Wochenschrift·1998·Klinik fü, Germany·View original on PubMed →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: [Cyclosporin A therapy in a cat with pure red cell aplasia].
- Species:
- cat
Plain-English summary
A 1-year-old male cat was brought in for severe anemia, showing very low red blood cell levels. Tests ruled out common viral infections, and further examination revealed that his bone marrow was not producing red blood cells properly. The veterinarian started treatment with cyclosporin A, an immunosuppressive medication, along with prednisolone, which helped the cat's body start producing red blood cells again. After five months of treatment, the cat's blood levels returned to normal, and he was much healthier overall.
People also search for: cat anemia treatment · cyclosporin A for cats · why is my cat lethargic · cat autoimmune disease symptoms
Abstract
The case of a one year and 7 months old castrated male cat suffering from severe, non regenerative anaemia (packed cell volume: 8.6%; reticulocyte count: 1/1000) is presented. A combined ELISA-test for feline leukaemia virus antigen and antibodies against feline immunodeficiency virus was negative. Using indirect Coomb's test IgM as well as the complement component C3b could be demonstrated on the erythrocytes. Cytological investigation of the bone marrow revealed a selective, nearly complete aplasia of the erythropoiesis. Immunosuppressive therapy with cyclosporin A (6.25 mg/kg BW orally, twice daily) and prednisolone (initially 5 mg/kg BW intravenously, twice daily) from the 9th day on led to a distinct regeneration of erythropoiesis with reticulocyte counts up to 126/1000 (341.000/microliter) and normalisation of the red blood picture as well as the general state of health. The therapy with cyclosporin A was continued for five months, reducing the dosis after 30 days to 6.25 mg/kg BW orally once daily corresponding to an extremely high blood level of cyclosporine A. At control examinations 24 and 63 days after depositing therapy all parameters of the red blood picture were within the reference range. This case report indicates that pure red cell aplasia can be due to an autoimmune process in cats also as well.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/9880939/