Peer-reviewed veterinary case report
Cytology for diagnosing lymphoma in dogs - pros and cons
By Sapierzyński, R et al.·Published in Polish journal of veterinary sciences·2016·View original on PubMed →
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Original publication title: Cytodiagnostics of canine lymphomas - possibilities and limitations.
- Species:
- dog
Plain-English summary
A dog with swollen lymph nodes was diagnosed with lymphoma, a type of cancer that is common in dogs. Instead of a more invasive biopsy, the veterinarian used a fine-needle aspiration to collect a sample for testing, which is less harmful and often just as effective for diagnosis. This method is increasingly recommended because it can accurately identify the type of lymphoma and help guide treatment options. With the right approach, many dogs with lymphoma can receive targeted therapies that improve their chances of recovery.
People also search for: dog swollen lymph nodes · lymphoma diagnosis in dogs · fine-needle aspiration for dog cancer · dog cancer treatment options
Abstract
Malignant lymphomas are one of the most common malignant tumours occurring in dogs. The basic method of lymphoma diagnosis in human, as well as in canine oncology is histopathology supported by immunohistochemistry. It was suggested that in veterinary medicine excisional biopsy of lymph node and histopathology should be considered only where the cytologic diagnosis is equivocal or needs to be confirmed. There are at least three basic reasons for which cytological examination ought to be accepted as a sufficient and reliable diagnostic method for lymphoma in dogs. Firstly, most dog owners consider the fine-needle biopsy as an acceptable non-harmful method of sample collection. Secondly, an increasing number of studies recommend cytology as an accurate test for diagnosing and subtyping canine lymphoma. Finally, the vast majority of canine lymphoma subtypes belong to 4-5 categories characterized by a typical cytological picture. Immunocytochemical staining of cytological smears gives new diagnostic possibilities, such as detection of markers better characterizing given growth or a potential goal for target therapy in individual cases (for example inhibitors of platelet-derived growth factor).
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/27487521/