Peer-reviewed veterinary case report
Chromosome changes found in malignant melanoma of a Dachshund dog
By Mayr, B et al.·Published in Journal of comparative pathology·1992·Institute for Animal Breeding and Genetics·View original on PubMed →
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Original publication title: Cytogenetic studies in a canine malignant melanoma.
- Species:
- dog
Plain-English summary
A 13-year-old male rough-haired Dachshund was diagnosed with malignant melanoma, a type of skin cancer. Tests on the tumor cells revealed an unusual number of chromosomes, which can indicate aggressive cancer behavior. The findings included several abnormal chromosome structures. While the study focused on the genetic aspects of the tumor, it highlights the complexity of this type of cancer in dogs. Treatment options for malignant melanoma often include surgery, chemotherapy, or immunotherapy, so discussing these with your veterinarian is important.
People also search for: dog skin cancer treatment · Dachshund melanoma symptoms · canine cancer chromosome abnormalities
Abstract
In a 13-year-old, male rough-haired Dachshund with a malignant melanoma, cytogenetic evaluation of tumour cells showed hyperdiploidy (79 to 81 chromosomes) in 50 per cent of the metaphases. Several bi-armed chromosomes (centric fusions, one isochromosome and two unidentified markers) were observed.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/1602064/