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Peer-reviewed veterinary case report

Dog with firm skin lump diagnosed as keloidal fibrosarcoma

By Little, Liz K & Goldschmidt, Michael·Published in Veterinary clinical pathology·2007·Department of Pathobiology, United States·View original on PubMed

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Original publication title: Cytologic appearance of a keloidal fibrosarcoma in a dog.

Species:
dog

Plain-English summary

A 5-year-old neutered male mixed-breed dog was brought to the vet because of a firm, nodular mass about the size of a pea on his left side that had been there for two weeks. Tests showed that the mass was made up of abnormal cells, leading to a diagnosis of keloidal fibrosarcoma, a type of skin cancer. While the report details the specific characteristics of the cells, the main concern for pet owners is that this type of tumor can be serious. Treatment options typically include surgical removal, and early intervention is key for the best outcome.

People also search for: dog skin lump treatment · keloidal fibrosarcoma in dogs · mixed-breed dog tumor symptoms

Abstract

A 5-year-old neutered male, mixed-breed dog was presented with a single 4-mm, nodular, firm, haired subcutaneous mass on the left flank that had been present for approximately 2 weeks. Cytologic preparations of the mass revealed many spindle cells, few mast cells, rare eosinophils, rare macrophages, abundant hyalinized collagen, and moderate numbers of erythrocytes. The spindle cells were oval to fusiform, with oval nuclei, finely stippled to lacy chromatin, 1-5 variably sized prominent nucleoli, and moderate to abundant cytoplasm with indistinct cell borders, wispy cytoplasmic extensions, and occasionally, fine magenta granulation. The cell population exhibited moderate anisocytosis, moderate anisokaryosis, and rare binucleation. The eosinophilic material occurred both in large angular aggregates with blunt ends and in amorphous aggregates with fine wispy projections. Histologic findings were consistent with a keloidal fibrosarcoma. To the authors' knowledge, this report is the first to describe the cytomorphologic characteristics of a keloidal fibrosarcoma in a dog.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/18041704/