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Peer-reviewed veterinary case report

Brain tumor with seizures in a 10-year-old German Wirehaired Pointer

By Alonso, Flavio H et al.·Published in Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·2025·Veterinary Medical Teaching Hospital, United States·View original on PubMed

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Original publication title: Cytology and histology of a high-grade oligodendroglioma with embryonal features in a dog.

Species:
dog

Plain-English summary

A 10-year-old male German Wirehaired Pointer was brought to the vet after experiencing sudden cluster seizures. Tests, including an MRI, showed a bleeding mass in the left side of his brain. During surgery, the vet removed the abnormal tissue, which was later identified as a high-grade oligodendroglioma, a type of brain tumor. Unfortunately, due to the aggressive nature of this tumor, the prognosis is often poor, and further treatment options would need to be discussed with a veterinarian.

People also search for: dog seizures causes · brain tumor in dogs · treatment for dog oligodendroglioma

Abstract

A 10-y-old castrated male German Wirehaired Pointer dog was presented for referral evaluation of a brain mass and craniotomy. Pertinent history included acute onset of cluster seizures; the systemic physical examination was largely unremarkable. Thorough laboratory and imaging screening ruled out extracranial causes for the presenting clinical signs. MRI revealed a hemorrhagic and strongly contrast-enhancing mass in the left frontal lobe. Upon craniotomy, the lesion was abnormal cortical parenchyma with surrounding malacic tissue, which was excised and submitted for microscopic analyses. Cytologic examination of a squash preparation of the mass revealed a mildly inflamed and hemorrhagic neoplasm, with oligodendroglioma or an embryonal CNS neoplasm as primary differential diagnoses. Histopathology with immunohistochemistry confirmed a high-grade oligodendroglioma with embryonal morphology.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/40237443/