Data on characteristics of simplicia, phytoconstituents, and antioxidant activity of <i>Moringa oleifera</i> leaves ethanol extract.

Abstract

The article reports data on the chemical and pharmacological characteristics of <i>Moringa</i> oleifera simplicia and ethanol extract consisting of water content, acid-insoluble ash content, microbial contamination, heavy metal contamination, phytochemical analysis, TLC analysis, chemical profiling using LC-MS/MS, and the antioxidant activity. The <i>M. oleifera</i> leaves simplicia meet quality standards, except for ash content that exceeds the specified standards. Qualitative phytochemistry indicates that the ethanol extract of <i>M. oleifera</i> leaves contains flavonoids, tannins, and steroids. In total of 39 phytoconstituents were tentatively identified; the top 10 active compounds with the highest relative abundance percentage (%) are 4-undecylbenzenesulfonic acid (4,83), apigetrin (3,34), quercetin-3β-D-glucoside (3,28), D-(-)-quinic acid (1,69), corchorifatty acid F (1,52), 4-hydroxybenzaldehyde (1,47), isopropylmalic acid (1,17), 13(<i>S</i>)-HOTrE (1,08), astragalin (0,99), and D-(+)-phenyllactic acid (0,70). The ethanol extract of <i>M. oleifera</i> leaves contained a total phenolic content 7728,02 mg/kg, total flavonoids as quercetin content 1,19%, and antioxidant activity IC₅₀ 1422,45 mg/kg.