Peer-reviewed veterinary case report
DAV131A Protects Hamsters from LethalInfection Induced by Fluoroquinolones.
- Journal:
- Antimicrobial agents and chemotherapy
- Year:
- 2019
- Authors:
- Saint-Lu, Nathalie et al.
- Affiliation:
- Da Volterra · France
- Species:
- rodent
Abstract
Fluoroquinolone treatments induce dysbiosis of the intestinal microbiota, resulting in loss of resistance to colonization by exogenous bacteria such asthat may cause severe diarrhea in humans and lethal infection in hamsters. We show here that DAV131A, a charcoal-based adsorbent, decreases the intestinal levels of the fluoroquinolone antibiotics levofloxacin and ciprofloxacin in hamsters, protects their intestinal microbiota, and prevents lethal infection by.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/31636067/