Peer-reviewed veterinary case report
Efficacy of fluoroquinolones against Leptospira interrogans in a hamster model.
- Journal:
- Antimicrobial agents and chemotherapy
- Year:
- 2007
- Authors:
- Griffith, Matthew E et al.
- Affiliation:
- Infectious Disease Service · United States
- Species:
- rodent
Abstract
Ciprofloxacin, gatifloxacin, and levofloxacin were evaluated for their abilities to prevent mortality in hamsters infected with a lethal inoculum of Leptospira interrogans serovar Portlandvere. Each agent produced a statistically significant survival advantage compared to no treatment and demonstrated survival similar to that seen with doxycycline therapy.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/17470646/