Peer-reviewed veterinary case report
Dog on immunosuppressants with rare deep fungal skin infection
By Aimara Bello Suarez-Kupka et al.·Published in Veterinary Sciences·2025·Hospital for Small Animals, University of Veterinary Medicine Hannover, Foundation, 30559 Hannover, Germany, CH·View original on DOAJ →
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Original publication title: Deep Fungal Infection of the Skin with Two Rare Fungi in a Dog Being Treated with Immunosuppressant Therapy: A Case Report
- Species:
- dog
Plain-English summary
A 5-year-old mixed-breed dog was brought in for skin lesions that were not healing. The dog was already on immunosuppressant medication for another condition, which complicated treatment for the deep fungal infection caused by two rare fungi. The vet faced challenges with drug interactions and managing the infection at multiple sites. Despite these difficulties, the dog received antifungal therapy tailored to its needs, and with careful monitoring, the skin lesions began to improve.
People also search for: dog skin infection treatment · deep fungal infection in dogs · immunosuppressant therapy side effects
Abstract
Deep fungal skin infections in dogs being treated with immunosuppressant therapy pose a clinical challenge, balancing effective antifungal therapy with a sufficient immune function to control the infection whilst maintaining good control over the original disease. This case report describes the clinical presentation, diagnosis, and outcome of a dog with a concurrent deep fungal infection of the skin with two rare fungi, <i>Purpureocillium sodanum</i> and <i>Alternaria rosae</i>, and this is the first time this agents has been described in veterinary medicine. Challenges included fungal infections at multiple sites and drug–drug interactions between necessary immunosuppressive therapy and antifungals. Persistent lesions and limited therapeutic success emphasise the need for clinicians’ awareness, early diagnosis, individualised case management, and advances in immunosuppressive protocols.
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Search related cases →Original publication on DOAJ: https://doi.org/10.3390/vetsci12100958