Peer-reviewed veterinary case report
Design and synthesis of sarolaner, a novel, once-a-month, oral isoxazoline for the control of fleas and ticks on dogs.
- Journal:
- Bioorganic & medicinal chemistry letters
- Year:
- 2016
- Authors:
- Curtis, Michael P et al.
- Affiliation:
- Department of Medicinal Chemistry · United States
- Species:
- dog
Abstract
Over the last decade, the isoxazoline motif has become the intense focus of crop protection and animal health companies in their search for novel pesticides and ectoparasiticides. Herein we report the discovery of sarolaner, a proprietary, optimized-for-animal health use isoxazoline, for once-a-month oral treatment of flea and tick infestation on dogs.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/26920802/