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Peer-reviewed veterinary case report

Design of a novel class of biphenyl CETP inhibitors.

Journal:
Bioorganic & medicinal chemistry letters
Year:
2010
Authors:
Lu, Zhijian et al.
Affiliation:
Department of Medicinal Chemistry · United States

Abstract

A new class of CETP inhibitors was designed and prepared. These compounds are potent both in vitro and in vivo. The most active compound (12d) has shown an ability to raise HDL significantly in transgenic mouse PD model.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/21041082/