Peer-reviewed veterinary case report
Rapid test detects canine parvovirus type 2c in dog stool samples
By Decaro, Nicola et al.·Published in Veterinary journal (London, England : 1997)·2010·Department of Veterinary Public Health, Italy·View original on PubMed →
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Original publication title: Detection of canine parvovirus type 2c by a commercially available in-house rapid test.
- Species:
- dog
Plain-English summary
A study tested a rapid test for canine parvovirus (CPV) using samples from dogs that were already confirmed to have the virus. The test was able to detect different variants of CPV, including the newer CPV-2c, with an accuracy of around 77-80%. However, if the test comes back negative, it's important to follow up with a more sensitive PCR test to confirm the results. This means that while the rapid test can be useful, it might not catch every case of parvovirus, so further testing may be needed if symptoms persist.
People also search for: dog parvovirus symptoms · rapid test for canine parvovirus · CPV-2c detection in dogs
Abstract
Diagnosis of canine parvovirus (CPV) infection is usually carried out by means of rapid immunochromatographic assays, but the ability of these tests to detect all CPV variants, including the recently identified CPV-2c, is still debated. To determine if the assays detect the different CPV variants, 201 CPV PCR-positive faecal samples or rectal swabs were tested using a commercially available in-house test. Specimens (CPV-2a, n=51; CPV-2b, n=50; CPV-2c, n=100), containing CPV DNA loads >10(5) DNA copies/mg faeces, as determined by real-time PCR, were selected from previous studies. The percentage of positive in-house tests was 80.4%, 78.0% and 77.0% for CPV types 2a, 2b and 2c, respectively, confirming the ability of the test to detect the new variant CPV-2c. However, considering the sensitivity limits of the in-house tests that have been observed previously, negative results from the in-house test kit should be confirmed by PCR-based methods.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/19410488/