Peer-reviewed veterinary case report
Determination of renal vascular resistance in dogs with diabetes mellitus and hyperadrenocorticism.
- Journal:
- The Veterinary record
- Year:
- 2008
- Authors:
- Novellas, R et al.
- Affiliation:
- Animal Medicine and Surgery Department · Spain
- Species:
- dog
Plain-English summary
In this study, researchers looked at 12 dogs with hyperadrenocorticism (a condition where the body produces too much cortisol) and three dogs with diabetes mellitus (a condition where the body has trouble regulating blood sugar), as well as four dogs that had both conditions. They measured something called renal vascular resistance, which relates to how well blood flows through the kidneys, and found that two dogs with hyperadrenocorticism and three with both conditions had high blood pressure. Overall, the dogs with these health issues had higher values for blood flow resistance and blood pressure compared to 27 healthy dogs, and these measurements were linked to their blood sugar levels. The study suggests that there is a connection between these conditions and increased blood pressure in dogs.
Abstract
In dogs, diabetes mellitus and hyperadrenocorticism are causes of hypertension associated with increases in vascular peripheral resistance. In human patients, the renal resistive index (ri) and pulsatility index (pi) are related to hypertension and diabetes and are used as indicators of disease severity. In this study the renal vascular resistance was measured in 12 dogs with hyperadrenocorticism, three with diabetes mellitus and four with both conditions, and the possible relationships between the two indices, blood pressure and biochemical parameters were investigated. Hypertension, defined as a systolic blood pressure more than 150 mmHg, was recorded in two of the dogs with hyperadrenocorticism and three of the dogs with hyperadrenocorticism and diabetes. The overall mean values for ri, pi and systolic blood pressure were higher in the diseased group of dogs than in 27 healthy dogs, and both indices were correlated with blood glucose concentration.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/19011245/