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Peer-reviewed veterinary case report

Dog developed diabetes after corticosteroid and methylprednisolone

By Jeffers, J G et al.·Published in Journal of the American Veterinary Medical Association·1991·Department of Dermatology School of Veterinary Medicine, United States·View original on PubMed

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Original publication title: Diabetes mellitus induced in a dog after administration of corticosteroids and methylprednisolone pulse therapy.

Species:
dog

Plain-English summary

An 8-year-old female Chow Chow developed diabetes after receiving a special treatment with methylprednisolone for skin lesions caused by pemphigus foliaceus, an autoimmune skin condition. Just a week after starting the treatment, blood and urine tests confirmed the diabetes. Fortunately, the dog has been well-managed as a diabetic for three years since then. To keep the skin condition under control, she is now given a lower dose of prednisone every other day, which has helped maintain her skin health.

People also search for: Chow Chow diabetes treatment · pemphigus foliaceus in dogs · prednisone for dog skin problems

Abstract

An 8-year-old ovariohysterectomized Chow Chow was referred because of dermatologic lesions diagnosed as pemphigus foliaceus. Intolerance to orally administered corticosteroids necessitated the use of methylprednisolone pulse therapy. One week after treatment, diabetes mellitus was diagnosed on the basis of blood and urine test results. For 3 years after treatment, the dog has remained a well-regulated diabetic. Complete remission of pemphigus foliaceus is maintained by alternate-day, orally administered prednisone (0.5 mg/kg of body weight).

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/1885333/