Peer-reviewed veterinary case report
Canine parvovirus-2 infection in South Gujarat dogs and diagnosis
By Sharma, Kishan Kumar et al.·Published in Acta Veterinaria Brno·2018·View original on Crossref →
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Original publication title: Diagnosis and characterization of canine parvovirus-2 affecting canines of South Gujarat, India
- Species:
- dog
Plain-English summary
A group of puppies in South Gujarat, India, were diagnosed with canine parvovirus-2 (CPV-2) after showing symptoms of severe diarrhea. Out of 73 samples tested, 35 were confirmed positive for CPV-2, with most cases occurring in unvaccinated puppies, particularly Labradors. The study found that a new mutant strain of CPV-2b was present in the area, highlighting the importance of vaccination and monitoring for this virus. Treatment typically involves supportive care, and early detection is crucial for recovery.
People also search for: puppy diarrhea causes · canine parvovirus symptoms · Labrador parvovirus treatment · puppy vaccination importance · CPV-2 outbreak in India
Abstract
The present study was carried out in the region of South Gujarat, India, to determine the prevalence and predisposing factors of canine parvovirus-2 (CPV-2) infection in acute gastroenteritis of pups. Further, haemagglutination (HA) test, enzyme linked immunosorbent assay (ELISA), polymerase chain reaction (PCR) and rapid immunochromatography test were compared for diagnosis and prevalent CPV-2 types were ascertained. A total of 73 diarrhoea samples were collected and out of those 32, 33 and 35 were found positive via HA, ELISA and PCR, respectively. In rapid test, 26/52 samples were found positive. Among different age-groups, 11/24 and 13/21 animals were positive in pups aged 4–8 and 8–12 weeks, respectively. All but one (34/35) positive samples were from unvaccinated animals. Labrador was found to be the most susceptible breed (n = 13) to infection. Considering PCR as the best test, 47.94% (35/73) prevalence of CPV was recorded. Among PCR positive samples, 3 and 32 belonged to type CPV-2a and CPV-2b, respectively. Type CPV-2c was not detected among the examined samples. Sequencing analysis of 9/10 CPV-2b isolates revealed single nucleotide polymorphism (SNP) (A-G) at position 4106 (alanine to threonine) and suggested the occurrence of mutant, new CPV-2b in this area. As other major pathogen canine coronavirus was detected in 7/38 CPV negative samples. Conclusively, CPV-2 infection was detected in 47.97% cases of AGE of pups which warrants search for other pathogens in the diagnostic procedure. This work is among the few recent reports which depict the occurrence of a novel mutant (new CPV-2b) in India.
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Search related cases →Original publication on Crossref: https://doi.org/10.2754/avb201887030247