Peer-reviewed veterinary case report
Shear wave ultrasound and kidney disease markers in dogs
By Cho, Hyun et al.·Published in Journal of veterinary science·2023·Department of Veterinary Medical Imaging, South Korea·View original on PubMed →
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Original publication title: Diagnostic assessment of two-dimensional shear wave elastography in relation to dimethyl arginine levels in dogs with chronic kidney disease.
- Species:
- dog
Plain-English summary
A group of dogs with chronic kidney disease (CKD) underwent a special test called two-dimensional shear wave elastography (2D SWE) to see if it could help identify kidney stiffness and relate it to a specific blood marker, symmetric dimethyl arginine (SDMA). The results showed that while there was a slight connection between SDMA levels and kidney stiffness, the test couldn't reliably tell the difference between dogs with healthy kidneys and those with early CKD. However, it might still be useful for tracking changes in kidney function over time.
People also search for: dog chronic kidney disease symptoms · SDMA levels in dogs · kidney function tests for dogs
Abstract
BACKGROUND: In veterinary medicine, previous studies regarding the diagnostic performance of shear wave elastography (SWE) in chronic kidney disease (CKD) are not consistent with each other. Moreover, there has been no study evaluating the relationship between symmetric dimethyl arginine (SDMA) concentration and renal shear wave velocity (SWV) using two-dimensional SWE (2D SWE) in dogs with CKD. OBJECTIVES: This study aimed to evaluate the diagnostic capability of 2D SWE in dogs with CKD and to assess the relationship between renal SWV and SDMA concentration. METHODS: Dogs with healthy kidneys and dogs with CKD underwent 2D SWE and SDMA assay. Renal stiffness was estimated as renal SWV in m/s. RESULTS: SDMA concentration had a weak positive correlation with the left (= 0.338,= 0.022) and right renal SWV (= 0.337,= 0.044). Renal SWV was not significantly different between healthy kidney and CKD groups in the left (= 0.085) and right (= 0.171) kidneys. CONCLUSIONS: 2D SWE may could not distinguish between dogs with healthy kidney and dogs with early stage of CKD, but it would be useful for assessing the serial change of renal function in dogs.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/37904637/