Peer-reviewed veterinary case report
Digital squamous cell cancer in large dark-haired dogs' toes study
By Belluco, S et al.·Published in Veterinary pathology·2013·Service d'Anatomie Pathologique, France·View original on PubMed →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: Digital squamous cell carcinoma in dogs: epidemiological, histological, and immunohistochemical study.
- Species:
- dog
Plain-English summary
A 10-year-old Beauceron was diagnosed with squamous cell carcinoma, a type of skin cancer that often affects the toes in dogs. This breed, along with the Briard, was found to be more prone to this condition, especially in dark-haired, large, and giant breeds. The cancer was more common in the front legs than the back legs, and while some dogs showed signs of metastasis (spread of cancer), the overall outcome did not seem to depend on specific tumor characteristics. Treatment options were not detailed, but monitoring for new tumor development is important for affected dogs.
People also search for: dog toe cancer treatment · squamous cell carcinoma in dogs · why is my dog limping on front leg · Beauceron skin problems · dog cancer prognosis
Abstract
Squamous cell carcinoma represents 47.4% of all malignant canine digital lesions, but despite its frequency, there are few published studies available. Pathology submission records of 154 cases and follow-up of 49 animals were analyzed. On the 49 cases, histological evaluation was performed of the differentiation degree, mitotic index, presence of emboli, and immunohistochemical expression of vimentin and E-cadherin. The mean (SD) age of affected animals was 10.2 (2.3) years; no sex predisposition was recorded. Beauceron and Briard were 2 new overrepresented breeds. Dark-haired animals comprised 97 of 105 (92%); 94 dogs of 125 (75.2%) belonged to large and giant breeds. The forelimb was affected twice more than the hind limb. Probable metastases were observed in 4 dogs; new tumor development was recorded in 11 of 49 (22.4%). Epidemiologic factors, histological grade, mitotic index, and expression of immunohistochemical markers seemed not to be related to the clinical outcome.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/23735617/