Peer-reviewed veterinary case report
Disseminated Acanthamoeba infection in a 1-year-old dog
By Dubey, J P et al.·Published in Veterinary parasitology·2005·United States Department of Agriculture, United States·View original on PubMed →
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Original publication title: Disseminated Acanthamoeba sp. infection in a dog.
- Species:
- dog
Plain-English summary
A one-year-old dog was diagnosed with a serious infection caused by Acanthamoeba, a type of free-living amoeba. The infection affected multiple organs, including the brain, heart, and kidneys, leading to severe inflammation. The diagnosis was confirmed through various tests, including tissue analysis and genetic testing. Unfortunately, the abstract does not provide information on the treatment or outcome for this dog.
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Abstract
Several species of free-living amoebae can cause encephalomyelitis in animals and humans. Disseminated acanthamoebiasis was diagnosed in pyogranulomatous lesions in brain, thyroid, pancreas, heart, lymph nodes, and kidney of a one-year-old dog. Acanthamoeba sp. was identified in canine tissues by conventional histology, by immunofluorescence, by cultivation of the parasite from the brain of the dog that had been stored at -70 degrees C for two months, and by PCR. The sequence obtained from the PCR product from the amoeba from the dog was compared to other sequences in the Acanthamoeba sp. ribosomal DNA database and was determined to be genotype T1, associated with other isolates of Acanthamoeba obtained from granulomatous amebic encephalitis infections in humans.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/15740854/