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Peer-reviewed veterinary case report

Disseminated blastomycosis causing eye and paw swelling in young dog

By Garofalo, Jessica·Published in The Canadian veterinary journal = La revue veterinaire canadienne·2022·Ontario Veterinary College, Canada·View original on PubMed

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Original publication title: Disseminated blastomycosis in a 1-year-old, male golden retriever-poodle crossbred dog.

Species:
dog

Plain-English summary

A 1-year-old male golden retriever-poodle mix was brought to the vet with eye irritation and discharge after a trip to Muskoka, Ontario. Despite initial treatment, his condition worsened, leading to a swollen toe and further tests that revealed a serious fungal infection called blastomycosis affecting his lungs and lymph nodes. He was started on antifungal medication, but after 11 days, he developed neurological issues and was ultimately euthanized. The diagnosis was confirmed after his passing.

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Abstract

A 1-year-old male golden retriever-poodle crossbred dog was brought to a veterinary clinic with a 1-month travel history to Muskoka, Ontario and a 1-week history of left eye irritation and ocular discharge. Ophthalmic examination and blood analysis revealed bilateral uveitis with a normal complete blood (cell) count and biochemistry panel. Symptomatic treatment was administered with no improvement observed and the dog returned 2 weeks later for assessment of a draining swelling of the left hind 4th digit. Clinical examination of thoracic radiographs and abdominal ultrasound showed evidence of disseminated blastomycosis characterized by pulmonary lesions, and multifocal lymphadenopathy. Biopsy of the draining lesion and cytological examination of an enlarged lymph node established diagnosis. The dog was started on a standard antifungal treatment protocol (itraconazole) but returned after 11 d of treatment with neurological signs including ataxia, paraparesis, left head tilt, and compulsive turning. Humane euthanasia was chosen and the diagnosis was confirmed at postmortem examination.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/35919470/