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Peer-reviewed veterinary case report

Disseminated Geosmithia argillacea infection in German Shepherd dog

By Grant, David C et al.·Published in Medical mycology·2009·Department of Small Animal Clinical Sciences, United States·View original on PubMed

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Original publication title: Disseminated Geosmithia argillacea infection in a German shepherd dog.

Species:
dog

Plain-English summary

A German Shepherd was diagnosed with a serious fungal infection caused by Geosmithia argillacea, which is a rare type of fungus. This infection affected the dog's entire body and is the first known case in pets or people. The dog was treated with antifungal medications, and while some common treatments were not effective, others like itraconazole and posaconazole showed promise. The outcome of the treatment is not specified, but the identification of effective medications is a positive step for managing this unusual infection.

People also search for: German Shepherd fungal infection treatment · dog systemic mycosis · Geosmithia argillacea in dogs

Abstract

We report a systemic mycosis in a German Shepherd dog caused by Geosmithia argillacea. Although this etiologic agent microscopically resembles a Penicillium species, and is histopathologically compatible with members of the genus Aspergillus, morphologic features and molecular characterization clearly separate it from these genera. This appears to be the first report of disseminated disease by this species in humans or animals. In vitro antifungal susceptibility testing suggests resistance to amphotericin B and voriconazole and susceptibility to caspofungin, itraconazole, and posaconazole.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/19169949/