Peer-reviewed veterinary case report
Cat with spleen cancer causing severe anemia and weight loss
By Ide, Kaori et al.·Published in The Journal of veterinary medical science·2009·Department of Veterinary Internal Medicine, Japan·View original on PubMed →
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Original publication title: Disseminated histiocytic sarcoma with excessive hemophagocytosis in a cat.
- Species:
- cat
Plain-English summary
A 10-year-old Japanese domestic cat was brought to the vet because it was not eating and losing weight. Tests showed the cat had severe anemia and low platelet counts, along with multiple masses in its spleen. After surgery to remove the spleen, the masses were found to be histiocytic sarcoma, a type of cancer. The cat was treated with medications prednisolone and lomustine, and it lived for 107 days after the diagnosis. Unfortunately, an autopsy later showed that the cancer had spread to other organs.
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Abstract
A 10-year-old Japanese domestic cat was presented with anorexia and weight loss. Severe anemia and thrombocytopenia were detected. Abdominal radiography and ultrasonography revealed the presence of multiple masses in the spleen. Cytological analyses of the masses revealed several atypical histiocytic cells and considerable hemophagocytosis. A splenectomy was performed, and the mass was diagnosed as histiocytic sarcoma on the basis of histopathological, cytochemical and immunohistochemical analyses. Further, abnormal hemophagocytosis was observed in the bone marrow. The cat was administered prednisolone and lomustine, and it survived for 107 days after admission. An autopsy revealed the presence of neoplastic histiocytic cells in the bone marrow, liver, pancreatic lymph node and glomeruli. This is the first case of histiocytic sarcoma in a cat to be reported in Japan.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/19578295/