Peer-reviewed veterinary case report
Inflammation in brain and spinal cord of dogs with granulomatous
By Maehara, Tomomi et al.·Published in The Journal of veterinary medical science·2009·Department of Veterinary Pathology, Japan·View original on PubMed →
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Original publication title: Distribution of the inflammatory lesions in the central nervous system of dogs affected with disseminated and ocular form of granulomatous meningoencephalomyelitis.
- Species:
- dog
Plain-English summary
An aged Maltese dog experienced unsteady walking for a month and suddenly died after having a seizure. Another aged Toy Poodle went blind very quickly and also died suddenly, likely from heart failure. Both dogs were found to have severe inflammation in their brains and spinal cords, leading to a diagnosis of granulomatous meningoencephalomyelitis (GME), a serious condition affecting the central nervous system. Unfortunately, both dogs did not survive, highlighting the severe impact of this disease on their health.
People also search for: dog seizure sudden death · dog blindness causes · granulomatous meningoencephalomyelitis in dogs · Toy Poodle sudden death · Maltese dog ataxia symptoms
Abstract
An aged Maltese dog (dog 1) showed gait ataxia for a month and suddenly died after convulsion. An aged Toy Poodle dog (dog 2) showed sudden blindness with unresponsive pupillary light reflexes and sudden death due to acute cardiac failure. Histological examination of the two dogs demonstrated severe granulomatous perivascular inflammation in the white matter throughout the central nervous system (CNS) including the brain and spinal cord. Based on the clinical and pathological findings, these dogs were diagnosed as granulomatous meningoencephalomyelitis (GME). In dog 2, the inflammatory changes predominated in the visual system such as the optic nerve, optic tract and optic radiation in the cerebrum (ocular form). Distribution pattern of the inflammatory lesions in the CNS was compared between the two dogs.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/19420859/