Peer-reviewed veterinary case report
Soft tissue sarcoma after vaccination in an Australian cat
By Burton, G & Mason, K V·Published in Australian veterinary journal·1997·Animal Skin and Allergy Clinic, Australia·View original on PubMed →
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Original publication title: Do postvaccinal sarcomas occur in Australian cats?
- Species:
- cat
Plain-English summary
A cat developed a soft tissue tumor in the shoulder area 1 to 7 months after receiving a vaccination. This tumor, which had features of both fibrosarcoma and malignant fibrous histiocytoma, was thought to arise from a reaction at the vaccination site. After surgery to remove the tumor, it came back, requiring more extensive surgery. Unfortunately, the cat was later euthanized two years later due to fluid buildup in the chest, although there was no sign of the tumor returning at that time. This case highlights a potential link between vaccinations and the development of certain tumors in cats.
People also search for: cat vaccination tumor · postvaccinal sarcoma in cats · cat soft tissue tumor treatment
Abstract
A soft tissue sarcoma occurred in the interscapular area of a cat, 1 to 7 months after vaccination at that site. The vaccine contained inactivated feline panleucopaenia virus combined with modified live feline herpesvirus and calicivirus. The tumour showed histological features of both fibrosarcoma and malignant fibrous histiocytoma. The tumour was observed to evolve from the site of a presumed postvaccinal granuloma. Local recurrence 6 weeks post excision necessitated more radical resection. Euthanasia was performed 2 years later when pleural effusion developed. The cause of effusion was not determined. There was no palpable evidence of local tumour regrowth at the time of euthanasia. A causal relationship between vaccination and sarcoma formation is considered based on the temporal association between the two events, the anatomical location of the tumour and histopathology consistent with postvaccinal sarcomas reported overseas. Six other vaccine site fibrosarcomas, potentially vaccine associated using the above criteria, are summarised.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/9066965/