Peer-reviewed veterinary case report
Do current CPV-2 and 2b vaccines protect puppies from new CPV-2c
By Larson, Laurie J & Schultz, R D·Published in Veterinary therapeutics : research in applied veterinary medicine·2008·Department of Pathobiological Sciences, United States·View original on PubMed →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: Do two current canine parvovirus type 2 and 2b vaccines provide protection against the new type 2c variant?
- Species:
- dog
Plain-English summary
A group of 12-week-old puppies that had never been vaccinated against canine parvovirus were given two different vaccines to see if they would protect against a new variant of the virus. The puppies that received the vaccines developed antibodies and were protected from getting sick when exposed to the virus, while all the puppies that did not receive the vaccine became ill, with half of them dying or needing to be euthanized. This shows that the vaccines were effective in protecting against both the original and new strains of canine parvovirus.
People also search for: puppy parvovirus vaccine effectiveness · canine parvovirus symptoms · what to do if my puppy has parvovirus
Abstract
Three groups (n=9 or 10) of 12-week-old canine parvovirus type 2 (CPV-2) antibody-negative puppies were vaccinated: one group with a product containing modified-live CPV-2b (Galaxy DA2PPv; Schering-Plough Animal Health), one group with a product containing modified-live CPV-2 (Continuum DAP, Intervet), and one group (controls) with sterile saline. All puppies receiving CPV-2 and CPV-2b vaccines developed antibody as determined by the hemagglutination inhibition assay. All groups of puppies were challenged with a combination of virulent CPV-2b and CPV-2c 5 weeks after vaccination. All puppies in the CPV-2 and CPV-2b vaccinated groups were protected from disease, whereas all control group puppies developed disease and 50% died or were euthanized. This study demonstrated that the CPV-2 and CPV-2b vaccine components of the Continuum DAP and Galaxy DA2PPv products, respectively, provided protection against the CPV-2b virus and also provided complete protection against the new CPV-2c variant.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/18597247/