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Peer-reviewed veterinary case report

Dopamine caused slow heart rate in two dogs under anesthesia

By Tsompanidou, P P et al.·Published in The Journal of small animal practice·2013·Companion Animal Clinic·View original on PubMed

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Original publication title: Dopamine-induced bradycardia in two dogs under isoflurane anaesthesia.

Species:
dog

Plain-English summary

Two dogs developed a sudden slow heart rate (bradycardia) during surgery while under isoflurane anesthesia after receiving a dopamine infusion to help with low blood pressure. The bradycardia was linked to a reflex response that can occur with this treatment. The situation was serious, but the dogs were monitored closely, and the veterinary team was able to manage the effects of the medication.

People also search for: dog surgery heart rate drop · isoflurane anesthesia side effects · dopamine infusion in dogs

Abstract

Dopamine is a commonly used positive inotropic agent for the treatment of hypotension in small animals. Two dogs that had undergone surgery, under isoflurane anaesthesia, developed a sudden and profound bradycardia when a dopamine infusion was administered. Bradycardia was attributed to the activation of the Bezold-Jarisch reflex, an inhibitory reflex, characterised by bradycardia and hypotension.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/23902368/