Peer-reviewed veterinary case report
FIV vaccine protects cats for 12 months against infection
By Huang, Chengjin et al.·Published in Journal of feline medicine and surgery·2010·Fort Dodge Animal Health Division of Wyeth, United States·View original on PubMed →
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Original publication title: Dual-subtype feline immunodeficiency virus vaccine provides 12 months of protective immunity against heterologous challenge.
- Species:
- cat
Plain-English summary
A group of cats was vaccinated with a dual-subtype feline immunodeficiency virus (FIV) vaccine and then exposed to a strain of the virus a year later to see if they were still protected. Out of the vaccinated cats, 10 out of 14 remained fully protected against the virus, while all of the unvaccinated control cats became infected. This suggests that the vaccine provides strong immunity for at least 12 months. If you're considering this vaccine for your cat, it appears to be effective in preventing FIV infection for a significant period.
People also search for: cat FIV vaccine effectiveness · feline immunodeficiency virus symptoms · how long does FIV vaccine last
Abstract
The duration of immunity of the dual-subtype feline immunodeficiency virus (FIV) vaccine, Fel-O-Vax FIV, for protection against subtype-B FIV was assessed in this study. Vaccinated cats along with controls were challenged with FIV(FC1), a subtype-B FIV strain, 54 weeks after the final vaccination, and monitored for 46-48 weeks for provirus and viral RNA in peripheral blood, provirus in lymphoid organs, and CD4:CD8 ratios. Results of provirus detection in peripheral blood and lymphoid organs and plasma viral RNA loads showed that 10/14 vaccinated cats were fully protected for 48 weeks against infection with FIV(FC1) whereas 5/5 controls were persistently infected with FIV(FC1). CD4:CD8 inversions were noted in association with FIV infection and viral loads were not significantly different between FIV infected controls and the unprotected vaccinated animals.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/20167521/