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Peer-reviewed veterinary case report

Swelling on cat's front paw caused by rare eccrine gland tumor

By Lombardo, Mara Sophie et al.·Published in Tierarztliche Praxis. Ausgabe K, Kleintiere/Heimtiere·2022·Institut f&#xfc, Germany·View original on PubMed

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Original publication title: [Eccrine adenoma in a cat].

Species:
cat

Plain-English summary

A one-year-old spayed female cat was brought to the vet because of a swelling on the footpad of her right front paw. The lump grew from 2 cm to 4 cm in just two months and eventually became ulcerated. After the vet surgically removed the tumor, tests showed it was a benign growth called an eccrine adenoma, which is a rare type of tumor that originates from sweat glands. The cat recovered well after the surgery, and no further treatment was needed.

People also search for: cat footpad swelling · cat tumor removal · eccrine adenoma in cats · cat paw lump treatment

Abstract

Tumors originating from eccrine glands are rare findings in dogs and cats. In most cases, the tumors are malignant, while adenomas are only reported anecdotally. In the present case, a one-year-old female, spayed cat was presented with a swelling of the footpad of the right forelimb. Initially, the mass possessed a diameter of 2 cm which progressed to 4 cm within the following two months. At the latter time point the tumor was ulcerated. After surgical removal, histological and immunohistochemical analyses were performed. Histologically, a well demarcated, nodular, multilobular mass was present. The cuboidal to columnar neoplastic cells were arranged in tubular and acinar structures. Tumor cells possessed large, round to oval nuclei with moderately distinct nucleoli. Mitotic figures averaged 0-1 per high power field. Additionally, large areas of chondroid metaplasia were evident. Immunohistochemically, neoplastic cells were positive for pan-cytokeratin AE1/AE3 whereas thyroid transcription factor 1 (TTF1) was not expressed. Based on the histological and immunohistochemical findings an adenoma of the eccrine glands was diagnosed.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/35523168/