Peer-reviewed veterinary case report
Metoclopramide does not lower early aspiration pneumonia risk
By Milovancev, Milan et al.·Published in Veterinary surgery : VS·2016·Department of Clinical Sciences·View original on PubMed →
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Original publication title: Effect of Metoclopramide on the Incidence of Early Postoperative Aspiration Pneumonia in Dogs with Acquired Idiopathic Laryngeal Paralysis.
- Species:
- dog
Plain-English summary
A group of 61 dogs with a condition called idiopathic laryngeal paralysis underwent surgery to help them breathe better. Half of the dogs received a medication called metoclopramide during and after the surgery, while the other half did not. After the surgery, 10% of the dogs developed aspiration pneumonia, which is a lung infection caused by inhaling food or liquid. The study found that metoclopramide did not reduce the risk of developing this pneumonia compared to the dogs that did not receive the medication.
People also search for: dog aspiration pneumonia treatment · metoclopramide for dogs · laryngeal paralysis surgery recovery
Abstract
OBJECTIVE: Evaluate the effect of a perioperative intravenous continuous rate infusion (CRI) of metoclopramide on the incidence of aspiration pneumonia in the short term postoperative period in dogs undergoing unilateral arytenoid lateralization. STUDY DESIGN: Prospective, randomized, multi-center clinical trial. ANIMALS: 61 client-owned dogs with idiopathic laryngeal paralysis and normal preoperative thoracic radiographs. METHODS: All dogs underwent unilateral arytenoid lateralization with a uniform anesthetic, analgesic, and management protocol. Dogs in the treatment group received an intravenous CRI of metoclopramide for 24 hours perioperative. All dogs were assessed for clinical signs of aspiration pneumonia based on the results of physical examination and owner interview up to the point of suture removal (10-14 days postoperative). Any dog with suspected aspiration pneumonia had thoracic radiographs performed. RESULTS: Six dogs developed aspiration pneumonia in the short term postoperative period (2/28 control dogs and 4/33 treated dogs), accounting for an overall frequency of 10% with no significant difference between control and treated dogs. No variables measured in the study were significantly different between control and treated dogs. CONCLUSIONS: Perioperative metoclopramide, at the doses used in this study, did not affect the incidence of aspiration pneumonia in the short term postoperative period in dogs with idiopathic laryngeal paralysis undergoing unilateral arytenoid lateralization.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/27270499/