Peer-reviewed veterinary case report
Midazolam caused balance problems in two older dogs with vestibular
By Jang, Min et al.·Published in Journal of the American Animal Hospital Association·2020·From Seoul National University College of Veterinary Medicine, South Korea·View original on PubMed →
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Original publication title: Effect of Midazolam on Vestibular Signs in Two Geriatric Dogs with Vestibular Disease.
- Species:
- dog
Plain-English summary
Two older dogs experienced sudden balance problems, like leaning and falling, after receiving a sedative called midazolam before surgery. One dog had a history of eye movement issues and head tilt, and after waking up from anesthesia, the balance problems returned but improved after receiving another medication called flumazenil. This suggests that the midazolam may have caused the balance issues in these dogs, who were already suspected to have a condition affecting their inner ear. Both dogs showed improvement after treatment.
People also search for: dog balance problems after anesthesia · midazolam side effects in dogs · treatment for dog vestibular disease
Abstract
An abrupt balance impairment, including leaning, falling, and rolling, occurred after IV administration of 0.2 mg/kg midazolam as a preanesthetic medication in two geriatric dogs with a history of nystagmus and head tilt. In the second case, leaning, falling, and rolling recurred after recovery from general anesthesia but gradually ceased after IV administration of 0.01 mg/kg flumazenil. These two cases suggest that the IV administration of midazolam was responsible for the balance impairment in dogs who were suspected to have idiopathic peripheral vestibular disease.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/32412341/