Peer-reviewed veterinary case report
How hemodialysis removes gadolinium in a dog with kidney injury
By Gordon, Daniel S & Langston, Cathy E·Published in Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)·2024·College of Veterinary Medicine, United States·View original on PubMed →
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Original publication title: Effective removal of gadolinium with hemodialysis in a dog with severe acute on chronic kidney injury.
- Species:
- dog
Plain-English summary
A 12-year-old female Yorkshire Terrier was brought in with severe kidney problems and neurological symptoms after receiving a gadolinium-based contrast agent for an MRI. To help her, the veterinarian used hemodialysis, a treatment that filters the blood, to remove the gadolinium from her system. After two sessions of hemodialysis, over 96% of the gadolinium was successfully eliminated, and her kidney function improved, although some neurological signs remained. This case shows that hemodialysis can be effective in removing certain contrast agents in dogs with kidney issues.
People also search for: dog kidney injury treatment · hemodialysis for dogs · gadolinium side effects in dogs
Abstract
OBJECTIVE: To describe the use of intermittent hemodialysis (IHD) to remove gadolinium (28.1 mg/kg dose) in a dog with severe kidney disease. CASE SUMMARY: A 12-year-old neutered female Yorkshire Terrier presented with severe acute-on-chronic kidney injury and concurrent neurological signs. The dog received extracorporeal therapy as part of management. Uremia improved after hemodialysis, but central nervous system signs persisted; therefore, a contrast-enhanced magnetic resonance imaging was performed, immediately followed by IHD. Two IHD treatments with a low-flux dialyzer were performed 1.5 and 25.75 hours after administration of gadolinium, with almost complete removal of gadolinium. More than 96% of gadolinium was removed with a single treatment. NEW OR UNIQUE INFORMATION PROVIDED: Extracorporeal therapy is effective at removing gadolinium-based chelated contrast agents and could be considered if magnetic resonance imaging is indicated in a patient with substantial kidney impairment. Alternatively, newer contrast agents that have been deemed safer in this patient population could be used.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/38971980/