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Peer-reviewed veterinary case report

Lotilaner effectiveness for treating botfly larvae in dogs

By Tortoriello, Rafaella et al.·Published in Revista brasileira de parasitologia veterinaria = Brazilian journal of veterinary parasitology : Orgao Oficial do Colegio Brasileiro de Parasitologia Veterinaria·2024·Programa de P&#xf3, Brazil·View original on PubMed

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Original publication title: Effectiveness of lotilaner on furuncular myiasis in dogs naturally infested with Dermatobia hominis (Diptera: Cuterebridae).

Species:
dog

Plain-English summary

Twelve dogs infested with live larvae from the botfly (Dermatobia hominis) were treated with a single oral dose of lotilaner (Credelio). After just six hours, the treatment was found to be about 80.6% effective in killing the larvae, with most showing signs of lethargy. While some larvae were still alive, they were not moving actively. This suggests that lotilaner is a promising option for treating this type of infestation in dogs.

People also search for: dog botfly treatment · lotilaner for dog larvae · how to treat Dermatobia hominis in dogs

Abstract

An evaluation was made of the larvicidal efficacy of lotilaner (Credeli®) in the treatment of dogs naturally infested with Dermatobia hominis larvae. A total of 12 dogs presenting at least three live D. hominis larvae were medicated. The animals were medicated orally with a single dose of no less than 20 mg/kg lotilaner. After drug administration, the animals remained at their homes, and observations were made to verify the larvicidal effect 6 hours after treatment. Live larvae were considered any parasite that exhibited motility after removal. For each animal was using the formula: 100 x [(total of live larvae before treatment - total live larvae after treatment) /total of live larvae before treatment] as criteria for evaluating lotilaner efficacy. A total of 98 larvae were counted in 12 dogs, with an average of 8.1 larvae per animal. The effectiveness of lotilaner was 80.6%. Nineteen larvae were found alive, albeit presenting hypomobility and lethargic behavior. However, note that the evaluation was performed just six hours after administration of the drug. Lotilaner administered orally in a single dose of 20 mg/kg showed 80.6% efficacy six hours after treating dogs naturally infested with D. hominis.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/39292068/