Peer-reviewed veterinary case report
Effectiveness of ozonized saline solution in the treatment ofspp. bacterial cystitis.
- Journal:
- Medical gas research
- Year:
- 2023
- Authors:
- Engelmann, Ana Martiele et al.
- Affiliation:
- Department of Small Animal Clinic · Brazil
- Species:
- dog
Plain-English summary
Bacterial cystitis, which is an infection of the bladder, is a common issue in both cats and dogs and often leads to the use of antibiotics. This can create problems because it may lead to bacteria that are resistant to multiple drugs. Researchers have been looking into ozone therapy as a potential treatment to help with these infections. In this study, a paraplegic dog with repeated bladder infections caused by a type of bacteria called Proteus was treated with ozonized saline solution, which is a special mixture of saltwater and ozone. The treatment involved either daily bladder washes for three days or multiple washes in one day. The results showed that doing several washes in one day was more effective at reducing the bacteria than spreading them out over several days.
Abstract
Bacterial cystitis is a common clinical problem among cats and dogs and is one of the main reasons for the administration of antimicrobials. This can cause serious damage to public and animal health, as this practice facilitates the selection of bacteria that are multidrug-resistant to antibiotics. In this context, it is urgent to understand and validate therapeutic modalities that complement antimicrobial treatment in cystitis cases. Ozone therapy has been proposed by scientists owing to the various mechanisms of action in a range of pathologies, both in human and animal medicine. This paper describes the bactericidal action of two different protocols of bladder irrigation with ozonized saline solution (59 μg/mL) in a paraplegic canine with recurrent bacterial cystitis caused by Proteus spp. In the first protocol, the bladder instillations were applied once a day for three consecutive days while in the second, successive lavages were performed throughout the day until a significant reduction in the presence of bacteria in the urine sediment. In this study, we were able to demonstrate that repeated bladder instillation within 24 hours was the most effective treatment for Proteus compared to a single instillation on successive days.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/36571382/