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Peer-reviewed veterinary case report

Ozonized saline solution for treating bacterial cystitis in pets

By Engelmann, Ana Martiele et al.·Published in Medical gas research·2023·Department of Small Animal Clinic, Brazil·View original on PubMed

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Original publication title: Effectiveness of ozonized saline solution in the treatment ofspp. bacterial cystitis.

Species:
dog

Plain-English summary

A paraplegic dog with recurrent urinary tract infections caused by Proteus bacteria was treated with ozonized saline solution to help clear the infection. The dog received multiple bladder flushes in one day, which proved to be more effective than daily treatments over several days. After the treatment, there was a significant reduction in bacteria found in the dog's urine. This approach may offer a promising alternative to traditional antibiotics for managing bacterial cystitis in pets.

People also search for: dog urinary tract infection treatment · ozonized saline for dog cystitis · paraplegic dog bladder infection care

Abstract

Bacterial cystitis is a common clinical problem among cats and dogs and is one of the main reasons for the administration of antimicrobials. This can cause serious damage to public and animal health, as this practice facilitates the selection of bacteria that are multidrug-resistant to antibiotics. In this context, it is urgent to understand and validate therapeutic modalities that complement antimicrobial treatment in cystitis cases. Ozone therapy has been proposed by scientists owing to the various mechanisms of action in a range of pathologies, both in human and animal medicine. This paper describes the bactericidal action of two different protocols of bladder irrigation with ozonized saline solution (59 μg/mL) in a paraplegic canine with recurrent bacterial cystitis caused by Proteus spp. In the first protocol, the bladder instillations were applied once a day for three consecutive days while in the second, successive lavages were performed throughout the day until a significant reduction in the presence of bacteria in the urine sediment. In this study, we were able to demonstrate that repeated bladder instillation within 24 hours was the most effective treatment for Proteus compared to a single instillation on successive days.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/36571382/