Peer-reviewed veterinary case report
Essential fatty acid supplements do not reduce seizures in dogs
By Matthews, Helen et al.·Published in Veterinary journal (London, England : 1997)·2012·Department of Veterinary Medicine, United Kingdom·View original on PubMed →
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Original publication title: Effects of essential fatty acid supplementation in dogs with idiopathic epilepsy: a clinical trial.
- Species:
- dog
Plain-English summary
A group of dogs with idiopathic epilepsy (a type of seizure disorder with no known cause) was given a daily supplement of essential fatty acids for 12 weeks to see if it would help control their seizures. Unfortunately, the study found that this supplement did not reduce the number or severity of seizures in these dogs. After the treatment period, the dogs were switched to a placebo for another 12 weeks, but there was no improvement noted during either phase.
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Abstract
The effects of essential fatty acid supplementation (EFA) on the control of idiopathic epilepsy in dogs were investigated in a blinded, placebo-controlled trial. Fifteen dogs were treated with triple purified Ω-3 oil containing 400 mg eicosapentaenoic acid, 250 mg docosahexaenoic acid and 22 mg vitamin E per 1.5 mL at a dose of 1.5 mL/10 kg once daily for 12 weeks, followed by a 12 week placebo period of supplementation with olive oil. Owners recorded seizure frequency and severity and any adverse events. EFA supplementation did not reduce seizure frequency or severity in dogs with idiopathic epilepsy.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/21641244/