Peer-reviewed veterinary case report
Spray-dried animal plasma effects on joint health in senior dogs
By Sun, Ziqi et al.·Published in Journal of animal science·2026·College of Animal Science and Technology, China·View original on PubMed →
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Original publication title: Effects of spray-dried animal plasma on inflammatory indicators, antioxidant capacity, and joint health in senior dogs.
- Species:
- dog
Plain-English summary
A group of senior dogs with osteoarthritis (OA) were given a special diet that included spray-dried animal plasma (SDAP) to see if it would help their joint health. After 42 days, the dogs on the SDAP diet showed improved protein digestion and lower levels of inflammation markers in their blood. They also had less lameness, meaning they were moving around better and experiencing less pain. This suggests that adding SDAP to their diet could be a helpful way to manage arthritis symptoms in older dogs.
People also search for: senior dog arthritis treatment · spray-dried animal plasma for dogs · improving joint health in older dogs
Abstract
Osteoarthritis (OA) is a chronic progressive degeneration joint disorder influenced by risk factors, such as genetics, age, and obesity. The purpose of this study was to investigate the effects of spray-dried animal plasma (SDAP) on nutrient digestibility, inflammatory responses, antioxidant capacity, and joint health in senior dogs with OA. Twenty-four dogs over 7 years old diagnosed with OA based on radiographic evidence and clinical signs were randomly assigned to 2 groups with 12 replicates per group. The following dietary treatments were administered: 1) CONTROL group: dogs with OA were provided a basal diet; 2) SDAP group: dogs with OA were provided a basal diet supplemented with 4% SDAP replacing chicken meal. The feeding trial lasted 42 days. This study found that the total tract apparent digestibility of crude protein was improved in the SDAP group compared to the CONTROL group (P < 0.05). Regarding antioxidant status, serum superoxide dismutase levels were increased, whereas malondialdehyde levels were decreased in the SDAP group compared to the CONTROL group on days 21 and 42 (P < 0.05). On d 42, serum interleukin-1β and metalloproteinase-13 levels in the SDAP group were significantly decreased compared to the CONTROL group (P < 0.05), alongside higher levels of serum interleukin-10 in the SDAP group (P < 0.05). Additionally, synovial fluid metalloproteinase-2 levels were significantly reduced in the SDAP group compared to the CONTROL group on day 42 (P < 0.05). Clinically, the lameness scores were significantly reduced in the SDAP group on day 42 relative to the CONTROL group (P < 0.05), indicating an alleviation of arthritis symptoms in dogs of the SDAP group. In conclusion, dietary supplementation with 4% SDAP could increase protein digestibility, alleviate inflammatory response, improve antioxidant properties, and relieve canine arthritis symptoms in senior dogs with OA. These findings support SDAP as a promising dietary intervention strategy for managing joint health in senior dogs.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/41698003/