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Peer-reviewed veterinary case report

How well NexGard treats fly larvae skin infection in dogs

By Pinilla, Juan Carlos & Pinilla, Andrea Isabel·Published in Veterinary parasitology, regional studies and reports·2024·Universidad de Santander·View original on PubMed

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Original publication title: Efficacy of Afoxolaner (NexGard®) in the treatment of furuncular myiasis caused by Dermatobia hominis fly (Diptera: Cuterebridae) in naturally infested dogs.

Species:
dog

Plain-English summary

A group of 25 dogs in Central and South America suffering from a skin condition caused by fly larvae were treated with a single dose of Afoxolaner (NexGard). This condition, known as furuncular myiasis, can cause significant discomfort and injury to the skin. After just 24 hours, all the larvae were found dead, and the treatment was effective in removing them from the dogs' wounds. The dogs showed no further signs of infestation after the treatment, indicating that Afoxolaner worked well against this specific type of fly larvae.

People also search for: dog skin problems fly larvae treatment · NexGard for dog myiasis · how to treat furuncular myiasis in dogs

Abstract

Furuncular myiasis due to Dermatobia hominis is the second most common skin diseases in dogs that live in tropical climates in Central and South America, causing discomfort and injuring in the connective tissue of the affected dog. Therefore, the objective of the study was to evaluate the effectiveness of Afoxolaner (Nexgard&#xae;) in the treatment of canine furuncular myiasis. Twenty-five dogs naturally infested with D. hominis were selected and received a single oral dose of 2.5&#xa0;mg/kg body weight of Afoxolaner (NexGard&#xae;). Larval infestations were classified as light (< 2 larvae), moderate (2 to 5 larvae) and severe (> 5 larvae), according to the number of larvae found in the wound. Twenty-four hours post-treatment, infested lesions were inspected, and all larvae were mechanically removed from the lesion site. All removed larvae were identified as D. hominis larvae and were found dead within 24&#xa0;h after treatment, demonstrating 100% larvicidal efficacy of Afoxolaner against D. hominis larvae.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/39025552/