Peer-reviewed veterinary case report
Procox oral suspension treats Isospora infection in kittens
By Petry, Gabriele et al.·Published in Parasitology research·2011·Bayer Animal Health GmbH, Germany·View original on PubMed →
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Original publication title: Efficacy of emodepside/toltrazuril suspension (Procox® oral suspension for dogs) against mixed experimental Isospora felis/Isospora rivolta infection in cats.
- Species:
- cat
Plain-English summary
A group of kittens infected with intestinal parasites Isospora felis and Isospora rivolta were treated with a medication called Procox, which contains emodepside and toltrazuril. After being treated with either a lower or higher dose, the kittens showed a significant reduction in the number of parasite eggs they were excreting. The higher dose was even more effective, reducing egg counts by up to 100%. The treatment was well tolerated, and no side effects were reported. This suggests that Procox can effectively help control these specific intestinal infections in young cats.
People also search for: kitten intestinal parasites treatment · Isospora felis infection in cats · Procox for kittens · cat diarrhea medication
Abstract
The coccidia Isospora felis and Isospora rivolta are intestinal parasites occurring worldwide in domestic cats. In young cats, they can be detected with higher prevalence.The effects of toltrazuril in the new combination product Procox(®) oral suspension for dogs containing 0.1 % emodepside and 2 % toltrazuril (0.9 mg emodepside + 18 mg toltrazuril per ml) were studied in eighteen kittens experimentally infected each with a total of 1 x 10(5) oocysts of a mixture of Isospora felis and Isospora rivolta. In the infectious material, the quantitative relation of I. felis and I. rivolta was about 1:5. Following a three-days period after infection, two groups of 6 kittens were treated during the prepatent period with either a single dose of 0.45 mg emodepside + 9 mg toltrazuril/kg body weight or 0.9 mg emodepside + 18 mg toltrazuril/kg body weight. A group of six kittens without any treatment served as a control. On day 5 post infection, the untreated kittens started the excretion of oocysts. Treatment with both toltrazuril doses significantly reduced oocyst excretion. Following the single higher dose, the reduction of oocysts of both Isospora spp. was more pronounced (96.7 % to 100 %) in comparison to the lower dose (57.2 % to 100 %). The Procox(®) application was well tolerated and no adverse events were seen with any of the applied dosages.When administered to kittens and as a single treatment during the prepatent period, Procox(®) is suitable to control the number of oocysts excreted in the faeces in case of an Isospora felis and Isospora rivolta infection.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/21739373/