Peer-reviewed veterinary case report
Milbemycin oxime cures most dogs with generalized demodicosis
By Holm, Birgit R·Published in Veterinary dermatology·2003·Department of Dermatology·View original on PubMed →
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Original publication title: Efficacy of milbemycin oxime in the treatment of canine generalized demodicosis: a retrospective study of 99 dogs (1995-2000).
- Species:
- dog
Plain-English summary
A group of 99 dogs with a skin condition called generalized demodicosis, which is caused by mites, were treated with a medication called milbemycin oxime. Most of the dogs were successfully cured after an average of about 2.3 months of treatment, with a higher success rate in younger dogs. The study found that starting treatment early improved the chances of recovery, while dogs with severe cases affecting their paws had a lower chance of being cured. Overall, 85% of the dogs treated showed no signs of mites after treatment.
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Abstract
Ninety-nine dogs diagnosed with generalized demodicosis were treated with milbemycin oxime. Cases diagnosed before two years of age were classified as juvenile-onset (53%) and those diagnosed after two years of age as adult-onset (47%). Dogs were considered cleared of mites when none could be demonstrated in scrapings and cured if no relapse was seen for 12 months. Eighty-five per cent (84/99) were cured with milbemycin oxime used for 1-6 months (mean 2.3 months) at a dosage of 0.5-1.6 mg kg-1 body weight (mean 0.75 mg kg-1). No significant difference in dosage or treatment time was seen between juvenile and adult cases. Chance of cure was significantly better in young animals (cured cases mean age 2.97 years) than in older animals (not cured cases mean age 8.02 years). Start of treatment early in the course of disease gave a significantly better chance of cure. Cases with severe pododemodicosis had less chance of a cure (9/11 not cured).
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/12895223/