Peer-reviewed veterinary case report
Efficacy of single-dose liposomal amphotericin B or micafungin prophylaxis in a neutropenic murine model of invasive pulmonary aspergillosis.
- Journal:
- Antimicrobial agents and chemotherapy
- Year:
- 2008
- Authors:
- Lewis, Russell E et al.
- Affiliation:
- University of Houston College of Pharmacy · United States
Abstract
In a neutropenic murine model of invasive pulmonary aspergillosis, prophylaxis with single doses of liposomal amphotericin B or micafungin at >or=5 mg/kg of body weight improved animal survival and suppressed the lung fungal burden for up to 7 days after infection, demonstrating the potential utility of infrequent dosing with these antifungals.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/18725439/