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Peer-reviewed veterinary case report

Electrochemotherapy safely treats squamous cell skin cancer in cats

By Spugnini, Enrico P et al.·Published in Veterinary journal (London, England : 1997)·2009·S.A.F.U. Department, Italy·View original on PubMed

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Original publication title: Electrochemotherapy for the treatment of squamous cell carcinoma in cats: a preliminary report.

Species:
cat

Plain-English summary

Nine cats with skin tumors called squamous cell carcinomas (SCC) were treated with a new method called electrochemotherapy, which combines a chemotherapy drug (bleomycin) with electric pulses to help the drug work better. Each cat received two treatments one week apart, and the side effects were minimal, mostly just some mild redness on their noses. Remarkably, seven of the cats showed complete improvement, with results lasting up to three years. This treatment appears to be a safe and effective option for cats suffering from these sun-related skin cancers.

People also search for: cat squamous cell carcinoma treatment · electrochemotherapy for cats · cat skin cancer symptoms · feline cancer treatment options

Abstract

Squamous cell carcinomas (SCC) of the skin are commonly described in cats. Reported treatments include surgery, radiation therapy and photodynamic therapy. This preliminary study reports on the management of these lesions combining the local administration of bleomycin (plus hyaluronidase for a more uniform distribution) with permeabilizing biphasic electric pulses. Nine cats with SCC graded T(2)-T(4) were treated over a 5 year period, and each cat received two sessions of electrochemotherapy (ECT) 1 week apart. The side effects of this treatment were minimal and limited to mild erythema of the nose. Seven of the cats (77.7%) had a complete response lasting up to 3 years. ECT seems to be a safe and effective option for the treatment of feline sun-induced squamous cell carcinomas and warrants further investigation.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/17904882/