Peer-reviewed veterinary case report
Epilepsy brain scan and tissue findings in Shetland sheepdog
By Hasegawa, Daisuke et al.·Published in The Journal of veterinary medical science·2002·Nippon Veterinary and Animal Science University, Japan·View original on PubMed →
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Original publication title: Electrocorticographic and histological findings in a Shetland sheepdog with intractable epilepsy.
- Species:
- dog
Plain-English summary
A Shetland sheepdog with severe epilepsy that didn't respond to medication was examined for more information about her condition. Despite tests like a brain scan and electroencephalography showing no issues, doctors implanted electrodes to monitor brain activity directly. This revealed abnormal spikes in a specific area of the brain, indicating where the seizures were coming from. Sadly, after the dog passed away, further examination showed damage in the brain regions associated with those spikes. This case highlights the challenges of treating epilepsy in dogs when standard medications fail.
People also search for: Shetland sheepdog epilepsy treatment · dog seizures not responding to medication · canine brain damage from seizures
Abstract
A Shetland sheepdog with epilepsy refractory to antiepileptic drugs was brought to the division of Veterinary Radiology at Nippon Veterinary and Animal Science University. Scalp electroencephalography and computed tomography was performed, but no abnormality was detected in either examination. To obtain detailed information, electrodes were implanted on the dura mater, and the electrocorticogram (ECoG) was recorded. In the ECoG, sporadic spikes were detected in the left parietal region, suggesting the presence of the epileptic focus in this region. After the dog's death, abnormalities of gyri were found in the region where spikes were detected in the ECoG. On histopathological examination, laminar malacia of the cingulate gyrus was observed. Furthermore, in the hippocampus, neuronal loss of pyramidal cells was observed.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/11999451/