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Peer-reviewed veterinary case report

Eosinophilia and eosinophilic infiltration into splenic B-cell high-grade lymphoma in a dog.

Journal:
The Journal of veterinary medical science
Year:
2010
Authors:
Tomiyasu, Hirotaka et al.
Affiliation:
Department of Veterinary Internal Medicine · Japan
Species:
dog

Abstract

A 13-year-old mixed-breed dog showing ascites, anorexia and anemia was found to have leukocytosis with marked eosinophilia, splenomegaly and hepatomegaly. The dog died 4 days after initial presentation and was diagnosed with splenic high-grade B-cell lymphoma at necropsy. Remarkable infiltrations of eosinophils were observed in spleen and liver tissues. The eosinophilia and infiltration of eosinophils into the lesions could have been associated with B-cell lymphoma because causes other than lymphoma were excluded. This is the first report of eosinophilia and eosinophilic infiltrations into neoplastic lesions in a dog with high-grade B-cell lymphoma.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/20467202/