Peer-reviewed veterinary case report
Dog with high eosinophils and spleen B-cell lymphoma signs
By Tomiyasu, Hirotaka et al.Ā·Published in The Journal of veterinary medical scienceĀ·2010Ā·Department of Veterinary Internal Medicine, JapanĀ·View original on PubMed ā
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Original publication title: Eosinophilia and eosinophilic infiltration into splenic B-cell high-grade lymphoma in a dog.
- Species:
- dog
Plain-English summary
A 13-year-old mixed-breed dog was brought to the vet with symptoms like fluid in the abdomen (ascites), loss of appetite (anorexia), and low red blood cell count (anemia). Sadly, the dog passed away just four days later, and a post-mortem exam revealed it had high-grade B-cell lymphoma affecting the spleen. The examination also showed a significant presence of eosinophils, a type of white blood cell, in the spleen and liver, which is unusual for this type of cancer. Unfortunately, despite the findings, the dog did not survive, highlighting the aggressive nature of this lymphoma.
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Abstract
A 13-year-old mixed-breed dog showing ascites, anorexia and anemia was found to have leukocytosis with marked eosinophilia, splenomegaly and hepatomegaly. The dog died 4 days after initial presentation and was diagnosed with splenic high-grade B-cell lymphoma at necropsy. Remarkable infiltrations of eosinophils were observed in spleen and liver tissues. The eosinophilia and infiltration of eosinophils into the lesions could have been associated with B-cell lymphoma because causes other than lymphoma were excluded. This is the first report of eosinophilia and eosinophilic infiltrations into neoplastic lesions in a dog with high-grade B-cell lymphoma.
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Search related cases āOriginal publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/20467202/