Peer-reviewed veterinary case report
Eosinophilic leukemia signs and diagnosis in a cat
By Sharifi, Hassan et al.·Published in Journal of feline medicine and surgery·2007·Department of Clinical Sciences·View original on PubMed →
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Original publication title: Eosinophilic leukaemia in a cat.
- Species:
- cat
Plain-English summary
A 14-year-old female domestic shorthair cat was brought in for a persistent fever, loss of appetite, vomiting, weight loss, and weakness. The veterinarian found signs of dehydration and an enlarged spleen, along with pale gums. Blood tests showed low red blood cell and platelet counts, and further examination revealed a high number of immature eosinophils, which are a type of white blood cell. Although the cat was diagnosed with eosinophilic leukemia, a rare blood cancer, the study highlights that advanced testing methods can help in diagnosing this condition more accurately.
People also search for: cat vomiting weight loss · cat leukemia symptoms · treatment for cat anemia · why is my cat weak and dehydrated
Abstract
A 14-year-old female domestic shorthair cat was presented to Tehran University Veterinary Teaching Hospital for a persistent fever, anorexia, intermittent vomiting, weight loss and weakness. The main clinical signs were pale mucous membranes, dehydration and splenomegaly. The complete blood count and serum biochemistry tests revealed non-regenerative anaemia, thrombocytopenia and increased alkaline phosphatase (ALP) activity. An enzyme-linked immunosorbent assay (ELISA) test for feline leukaemia virus was negative. Blood film and bone marrow examination revealed a large number of immature eosinophils with variable sizes and numbers of faintly azurophilic granules. Cytochemical staining of blood film demonstrated 70% positive cells for ALP activity. Four percent CD34 positive cells were detected by flow cytometry. As eosinophilic leukaemia is difficult to identify by light microscopy, well-defined diagnostic criteria and the use of flow cytometry and cytochemical staining can improve the ability to correctly diagnose this type of leukaemia in cats.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/17669677/