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Peer-reviewed veterinary case report

Young Jack Russell dog with eosinophilic lung disease and long

By Katajavuori, P et al.·Published in The Journal of small animal practice·2013·Small Animal Clinic Vihtivet·View original on PubMed

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Original publication title: Eosinophilic pulmonary granulomatosis in a young dog with prolonged remission after treatment.

Species:
dog

Plain-English summary

A 2-year-old Jack Russell terrier was brought in for a chronic cough and trouble exercising. Previous treatments with antibiotics and steroids only helped a little, so the vet ran more tests and found signs of a lung condition called eosinophilic pulmonary granulomatosis. After confirming the diagnosis, the dog was treated with steroids (prednisolone) and another medication (azathioprine). Within a month, the dog's lung issues improved significantly, and after 7 months of treatment, all medications were stopped. Now, 2.5 years later, the dog is still healthy and showing no signs of the condition.

People also search for: dog chronic cough treatment · Jack Russell lung problems · eosinophilic pulmonary granulomatosis in dogs

Abstract

A two-year-old Jack Russell terrier was presented for evaluation of chronic cough and exercise intolerance. Previous treatment with antibiotics and glucocorticoids had only partially ameliorated the clinical signs. During investigation, hypoxaemia, peripheral eosinophilia and an eosinophilic bronchoalveolar lavage fluid were noted. Thoracic radiographs revealed two ovoid clearly delineated soft-tissue opacities, one in the caudal segment of the left cranial lung lobe (diameter 26 mm) and the other in the right cranial lung lobe (diameter 20 mm). These findings were verified by computed tomography, which identified an additional smaller lesion (diameter 16 mm) dorsally in the right caudal lobe. Ultrasound-guided fine-needle aspiration samples confirmed the diagnosis of eosinophilic pulmonary granulomatosis and treatment with prednisolone and azathioprine was initiated. Within 1 month, granulomas were no longer detectable radiographically. All medication was discontinued after 7 months and currently, after 2·5 years, the dog remains free of clinical signs. To the authors' knowledge this is the first case report to describe prolonged remission from idiopathic canine eosinophilic pulmonary granulomatosis.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/23145526/