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Peer-reviewed veterinary case report

Dog with skin lymphoma and mouth sores treated with prednisolone

By Bhang, Dong Ha et al.·Published in Journal of veterinary science·2006·Department of Veterinary Internal Medicine, South Korea·View original on PubMed

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Original publication title: Epitheliotropic cutaneous lymphoma (mycosis fungoides) in a dog.

Species:
dog
LymphomaSkin & coatDogs

Plain-English summary

A 7-year-old male Yorkshire terrier was brought to the vet for a recurring skin issue that worsened over time, leading to red patches and sores in his mouth. After taking skin samples, the vet diagnosed him with a type of skin cancer called epitheliotropic cutaneous lymphoma. Blood tests showed high calcium levels, which can be a concern. The dog was treated with medications, including prednisolone and isotretinoin, but sadly, he passed away unexpectedly despite treatment.

People also search for: dog skin cancer treatment · Yorkshire terrier skin problems · what to do for dog with sores in mouth

Abstract

A seven-year-old castrated male Yorkshire terrier dog was presented for a recurrent skin disease. Erythematous skin during the first visit progressed from multiple plaques to patch lesions and exudative erosion in the oral mucosa membrane. Biopsy samples were taken from erythematous skin and were diagnosed with epitheliotropic T cell cutaneous lymphoma by histopathology and immunochemical stain. In serum chemistry, the dog had a hypercalcemia (15.7 mg/dl) and mild increased alkaline phosphatase (417 U/l). Immunohistochemistry was performed to detect parathyroid hormone-related peptide (PTH-rP) in epitheliotropic cutaneous lymphoma tissues but the neoplastic cells were not labeled with anti-PTH-rP antibodies. The patient was treated with prednisolone and isotretinoin. However, the dog died unexpectedly.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/16434861/