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Peer-reviewed veterinary case report

Dog with skin lymphoma and melanoma causing nodules and plaques

By M.I.P. Palumbo et al.·Published in Arquivo Brasileiro de Medicina Veterinária e Zootecnia·2015·View original on DOAJ

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Original publication title: Epitheliotropic cutaneous T-cell lymphoma associated with melanoma in a dog: case report

Species:
dog

Plain-English summary

A 7-year-old crossbred Boxer was brought in for skin problems, showing nodular lumps on its belly and unusual plaques on its back. Tests revealed two types of skin tumors: epitheliotropic cutaneous T-cell lymphoma and melanoma. The vet confirmed the diagnosis through a skin biopsy, which showed cancerous cells in both areas. Treatment options typically include chemotherapy or surgery, but the specific outcome for this dog wasn't detailed. It's important for pet owners to monitor any skin changes and consult their vet for proper diagnosis and treatment.

People also search for: dog skin lumps treatment · Boxer skin cancer symptoms · melanoma in dogs treatment

Abstract

Several types of tumors affect dogs' skin. Simultaneously occurring neoplasms with different histological patterns might be rarely present in the same animal. This paper describes the occurrence of epitheliotropic cutaneous T-cell lymphoma and melanoma in a dog. The animal had nodular lesions in the abdominal region and serpiginous plaques on the dorsal region of the trunk. Cytology evidenced malignant fusiform cells from the abdominal lesions as well as few round cells from the dorsal. The histopathological examination of the abdominal lesions showed dermis with polygonal to spindle-shaped neoplastic cells. The lesion of the dorsal region evidenced neoplastic round cells with generally distinct cell borders and a moderate amount of eosinophilic cytoplasm. Abdominal lesions were positive for Melan A. Dorsal and forelimb lesions were positive for CD3. This study reports the occurrence of epitheliotropic cutaneous T-cell lymphoma and malignant melanoma in a crossbred Boxer dog and discusses the importance of performing immunohistochemical profile to confirm the phenotype of the tumor.

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Original publication on DOAJ: https://doi.org/10.1590/1678-4162-7575